Cephalosporinase and penicillinase activities of a β-lactamase from Pseudomonas pyocyanea

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Cephalosporinase and penicillinase activities of a beta-lactamase from Pseudomonas pyocyanea.

1. Pseudomonas pyocyanea N.C.T.C. 8203 produces a beta-lactamase that is inducible by high concentrations of benzylpenicillin or cephalosporin C. Methicillin appeared to be a relatively poor inducer, but this could be attributed in part to its ability to mask the enzyme produced. Much of the enzyme is normally cell-bound. 2. No evidence was obtained that the crude enzyme preparation consisted o...

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prevalence of extended-spectrum and metallo β-lactamase production in ampc β-lactamase producing pseudomonas aeruginosa isolates from burns

conclusions a high prevalence of multiple β-lactamase production was observed among the ampc producers (60%), of which the majority co-produced ampc and mbl. the current study results showed correlation between β-lactamase production and the presence of antibiotic resistance genes in the isolates. results all isolates were multidrug resistant. ampc, esbl and mbl production were observed in 35 (...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1965

ISSN: 0006-2936

DOI: 10.1042/bj0960739